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It is helpful to restore volume by placing a catheterand administering maintenance fluids to the patient while the anesthetist prepares foranesthesia. Forcefulcontraction of this region under sympatheticstimulation (exercise, emotion) increases outflowresistance which has incapacitating haemodynamicconsequence. Improved diagnosis of periprosthetic joint infectionby multiplex PCR of sonication fluid from removed implants

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The prophylactic agent of choice is vera-pamil and has demonstrated efficacy, tolerability, andsafety in chronic prophylaxis (Leone et al., 2000). So in a sense, there was a genetic ?hole? (noTreg resistance to Th17 reprogramming, an autoimmune T cell-generating genetic mutation inTCR, or defective Treg genes) in the T cell immune system that allowed this type ofautoimmune reaction to occur.

It should be noted, however,that no uniform approach for recognition and managementof hypertension is available.

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